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Mailing Address:
Biochemistry
105 Engel Hall
Blacksburg, VA 24061-0308
email: Ben
Potters
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Research
Interests:
Cloning and expression of the genes encoding prokaryotic protein kinases,
protein phosphatases, and phosphoproteins and evaluation of their
functional properties (substrate specificity, functional consequences
of phosphorylation, etc.) in vitro. |
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Resesearch Description: Protein modification by the addition
and removal of a phosphate group (phosphorylation and dephosphorylation)
is a common process employed across all brances of life. For example
in humans the "fight or flight" response is dependent upon
phosphorylation. The long term research goal is to determine the complete
protein phosphorylation-dephosphorylation network in the cyanobacterium
Synechocystis sp. PCC 6803 and the thermophilic archaeon Sulfolobus
solfataricus. The understanding of these networks will enhance genetic
engineering of these organisms and will further the use of microorganisms
as environmental sensors. |
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